(89) Electrophilic amide allylation of 3-heterosubstituted oxindoles: a new route to spirocyclic 2-oxindole containing α-methylene-γ-butyrolactam structure
Tetsuya Sengoku, Daichi Hayashi, Masaki Takahashi and Hidemi Yoda
European Journal of Organic Chemistry, 2018, 1813-1820. (DOI: 10.1002/ejoc.201800084)

The key “electrophilic amide allylation” was accomplished by using acetoxy methacrylamides and tetrakis(triphenylphosphine)palladium as a catalyst, affording a variety of the amide allylated products in excellent yields.

 

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