1. Isolation and structure determination of bioactive peptides based on genome mining

New antibacterial peptide pentaminomycin C was isolated from a streptomycete (Kaweewan et al. J Antibiot. 2020)

2. Heterologous production of new bioactive peptide

New protease inhibitory peptide named grimoviridin was produced by heterologous co-expression of cryptic biosynthetic genes (Unno et al. Appl. Microbiol. Biotech. 2020 ).