Shizuoka University · Hamamatsu, Japan
We develop reactions that use visible light and electron transfer to control how radicals form and react. Our goal is to make it easier to build and modify complex organic molecules under mild conditions.
Explore our research · Master’s (ABP) · Current ABP undergraduates · PhD · Postdoctoral inquiries
Research and selected papers
Strong organic photoreductants
We use light to turn stable organic compounds into powerful single-electron reductants. For example, a base-activated Hantzsch ester can promote cleavage of C(sp³)–S bonds in alkyl benzothiazolyl sulfides, enabling desulfurative C–C coupling. We have applied this chemistry to the modification of natural products, including sugars.
Desulfurative coupling with base-activated Hantzsch esters
ChemCatChem 2025, 17, e202401427.
Radical switching
We use the same benzothiazolyl sulfide group to access different carbon radicals. Under oxidative photoredox conditions, radical formation occurs at the C–H bond next to sulfur. Under reductive conditions, cleavage of the C–S bond generates the radical. Switching between these pathways lets us form two C–C bonds in sequence at the same carbon atom.
Visible-light-induced radical switching for geminal C–C bond formation
Chem. Commun. 2025, 61, 9610–9613.
Hydrogen atom transfer catalysis
We explore structurally tunable sulfides as hydrogen atom transfer (HAT) catalysts. Photooxidation generates sulfur radical cations that can abstract hydrogen atoms from substrates such as alcohols, ethers, and hydrocarbons. This provides a route to direct C–H alkylation.
Sulfide catalysts for hydrogen atom transfer under photoredox conditions
Adv. Synth. Catal. 2026, 368, e70293.
More publications in Shizuoka University’s researcher database
Study or work with us
Prospective master’s students
Interested in doing a master’s research project in synthetic organic chemistry? Shizuoka University’s Asia Bridge Program (ABP) offers an English-taught master’s route in engineering for eligible international applicants. Our group is part of the Applied Chemistry and Biochemical Engineering Course in the Graduate School of Integrated Science and Technology.
Email Professor Sengoku to discuss potential research topics before applying. Tell us what you have studied, which of our research topics interests you, and when you hope to start. Check the current application guide for instructions on obtaining your prospective supervisor’s approval before you submit your application.
- ABP master’s admissions
- University application guides for ABP and other international master’s applicants
Current ABP undergraduates at Shizuoka University
If you are already studying at Shizuoka University through the undergraduate ABP, contact Professor Sengoku to ask about visiting the lab or discuss graduate study in the group.
Prospective PhD students
If you are interested in pursuing a PhD in the group, email Professor Sengoku before submitting a formal application. Include a CV, a brief summary of your research experience and interests, and your preferred start date. For application routes, eligibility, and deadlines, consult the Graduate School of Science and Technology.
Official doctoral admission requirements
Prospective postdoctoral researchers
Email Professor Sengoku to ask about current opportunities or discuss a fellowship proposal. Include a CV, a brief description of the research you would like to pursue, and your preferred start date. If you have a fellowship in mind, mention its name and application deadline.
Contact
Professor Tetsuya Sengoku
Synthetic Organic Chemistry Laboratory
Department of Applied Chemistry and Biochemical Engineering, Faculty of Engineering
Shizuoka University, Hamamatsu Campus
3-5-1 Johoku, Chuo-ku, Hamamatsu, Shizuoka 432-8561, Japan