Original Paper

  1. Kondo K, Yoshimi R, Apdila ET, Wakabayashi K, Awai K and Hisabori T (2023) Changes in intracellular energetic and metabolite states due to increased galactolipid levels in Synechococcus elongatus PCC 7942. Sci Rep 13: 259. Abstract
  2. Effendi DB, Sakamoto T, Ohtani S, Awai K and Kanesaki Y (2022) Possible involvement of extracellular polymeric substrates of Antarctic cyanobacterium Nostoc sp. strain SO-36 in adaptation to harsh environments. J Plant Res. 135: 771-784. Abstract
  3. Brotosudarmo THP, Setiyono E, Awai K and Pringgenies D (2021) Marine bacterium Seonamhaeicola algicola strain CC1 as a potential source for the antioxidant carotenoid, zeaxanthin. Ilmu Kelaut. 26: 215-224. Abstract
  4. Inada T, Machida S, Awai K and Suzuki I (2021) Production of hydroxy fatty acids and its effects on photosynthesis in the cyanobacterium Synechocystis sp. PCC 6803. Algal Res. 53: 102155. Abstract
  5. Apdila ET, Inoue S, Shimojima M and Awai K (2020) Complete replacement of the galactolipid biosynthesis pathway with plant-type pathway in the cyanobacterium Synechococcus elongatus PCC 7942. Plant Cell Physiol. 61: 1661-1668. Abstract
  6. Munawaroh HSH, Apdila ET and Awai K (2020) hetN and patS mutations enhance accumulation of fatty alcohols in the hglT mutants of Anabaena sp. PCC 7120. Front Plant Sci. 11: 804. Abstract
  7. Matsumoto T and Awai K (2020) Adaptations in chloroplast membrane lipid synthesis from synthesis in ancestral cyanobacterial endosymbionts. Biochem. Biophys. Res. Commun. 528: 473-477. Abstract
  8. Kobayashi K, Osawa Y, Yoshihara A, Shimojima M and Awai K (2020) Relationship between glycerolipids and photosynthetic components during recovery of thylakoid membranes from nitrogen starvation-induced attenuation in Synechocystis sp. PCC 6803. Front Plant Sci. 11: 432. Abstract
  9. Saito T and Awai K (2020) A polyketide synthase HglEA, but not HglE2, synthesizes heterocyst specific glycolipids in Anabaena sp. PCC 7120. J. Gen. Appl. Microbiol, 66: 99-105. Abstract 
  10. Setiyono E, Heriyanto, Pringgenies D, Shioi Y, Kanesaki Y, Awai K and Brotosudarmo THP (2019) Sulfur-containing carotenoids from a marine coral symbiont Erythrobacter flavus strain KJ5. Mar. Drugs 17(6): 349. Abstract
  11. Kanesaki Y, Setiyono E, Pringgenies D, Moriuchi R, Brotosudarmo THP, and Awai K (2019) Complete genome sequence of the marine bacterium Erythrobacter flavus strain KJ5. Microbiol Resour Announc 8: e00140-19. Abstract
  12. Suzuki Y, Suzuki T, Awai K and Shioi Y (2019) Isolation and characterization of a tandem-repeated cysteine protease from the symbiotic dinoflagellate Symbiodinium sp. KB8. PLoS ONE 14(1): e0211534. Abstract
  13. Shibata S, Arimura SI, Ishikawa T and Awai K (2018) Alterations of membrane lipid content correlated with chloroplasts and mitochondria development in Euglena gracilis. Front Plant Sci. 9: 370. Abstract
  14. Sato N and Awai K (2017) “Prokaryotic pathway” is not prokaryotic: Non-cyanobacterial origin of the chloroplast lipid biosynthetic pathway revealed by comprehensive phylogenomic analysis. Genome Biol Evol. 9: 3162-3178. Abstract
  15. Fujisawa T, Narikawa R, Maeda SI, Watanabe S, Kanesaki Y, Kobayashi K, Nomata J, Hanaoka M, Watanabe M, Ehira S, Suzuki E, Awai K and Nakamura Y (2017) CyanoBase: a large-scale update on its 20th anniversary. Nucleic Acids Res. 45: D551-D554. Abstract
  16. Maida E and Awai K (2016) Digalactosyldiacylglycerol is essential in Synechococcus elongatus PCC 7942, but its function does not depend on its biosynthetic pathway. Biochim Biophys Acta 1861:1309-14. Abstract
  17. Suzuki S, Awai K, Ishihara A, Yamauchi K (2016) Cold temperature blocks thyroid hormone-induced changes in lipid and energy metabolism in the liver of Lithobates catesbeianus tadpoles. Cell Biosci. 6:19. Abstract
  18. Awai K, Ohta H and Sato N (2014) Oxygenic photosynthesis without galactolipids. Proc. Natl. Acad. Sci. USA. 111:13571-13575. Abstract
  19. Halimatul HSM, Ehira S and Awai K (2014) Fatty alcohols can complement functions of heterocyst specific glycolipids in Anabaena sp. PCC 7120. Biochem. Biophys. Res. Commun. 450:178-83 Abstract
  20. Murakawa M, Shimojima M, Shimomura Y, Kobayashi K, Awai K and Ohta H (2014) Monogalactosyldiacylglycerol synthesis in the outer envelope membrane of chloroplasts is required for enhanced growth under sucrose supplementation. Front. Plant Sci. 5: 280 Abstract
  21. Hori K, Maruyama F, Fujisawa T, Togashi T, Yamamoto N, Seo M, Sato S, Yamada T, Mori H, Tajima N, Moriyama T, Ikeuchi M, Watanabe M, Wada H, Kobayashi K, Saito M, Masuda T, Sasaki-Sekimoto Y, Mashiguchi K, Awai K, Shimojima M, Masuda S, Iwai M, Nobusawa T, Narise T, Kondo S, Saito H, Sato R, Murakawa M, Ihara Y, Oshima-Yamada Y, Ohtaka K, Satoh M, Sonobe K, Ishii M, Ohtani R, Kanamori-Sato M, Honoki R, Miyazaki D, Mochizuki H, Umetsu J, Higashi K, Shibata D, Kamiya Y, Sato N, Nakamura Y, Tabata S, Ida S, Kurokawa K, Ohta H (2014) Klebsormidium flaccidum genome reveals primary factors for plant terrestrial adaptation. Nat. Commun. 5: 3978 Abstract
  22. Iketani A, Nakamura M, Awai K and Shioi Y (2013) A novel serine protease with caspase- and legumain-like activities from edible mushroom Flammulina velutipes. Fungal Biology 117:173-181. Abstract
  23. Wakahama T, Laza-Martínez A, Bin Haji Mohd Taha AI, Okuyama H, Yoshida K, Kogame K, Awai K, Kawachi M, Maoka T and Takaichi S (2012) Structural confirmation of a unique carotenoid lactoside, p457, in Symbiodinium sp. Strain NBRC 104787 isolated from a sea anemone and its distribution in dinoflagellates and various marine organisms. J. Phycol. 48:1392-1402. Abstract
  24. Fujisawa T, Narikawa R, Okamoto S, Ehira S, Yoshimura H, Suzuki I, Masuda T, Mochimaru M, Takaichi S, Awai K, Sekine M, Horikawa H, Yashiro I, Omata S, Takarada H, Katano Y, Kosugi H, Tanikawa S, Ohmori K, Sato N, Ikeuchi M, Fujita N and Ohmori M (2010) Genomic Structure of an Economically Important Cyanobacterium, Arthrospira (Spirulina) platensis NIES-39. DNA Res. 17: 85-103 Abstract
  25. Kobayashi K, Awai K, Nakamura M, Nagatani A, Masuda T and Ohta H (2009) Type B monogalactosyldiacylglycerol synthases are involved in phosphate starvation-induced lipid remodeling and are crucial for low-phosphate adaptation. Plant J. 57: 322-331. Abstract
  26. Awai K, Watanabe H, Benning C and Nishida I (2007) Digalactosyldiacylglycerol is required for better photosynthetic growth of Synechocystis sp. PCC6803 under phosphate limitation. Plant Cell Physiol. 48: 1517-1523. Abstract
  27. Lu B, Xu C, Awai K, Jones AD and Benning C (2007) A small ATPase protein of Arabidopsis, TGD3, involved in chloroplast lipid import. J. Biol. Chem. 282: 35945-35953. Abstract
  28. Awai K and Wolk CP (2007) Identification of the glycosyl transferase required for synthesis of the principal glycolipid characteristic of heterocysts of Anabaena sp. strain PCC 7120. FEMS Microbiol. Lett. 266: 98-102. Abstract
  29. Awai K, Xu C, Tamot B and Benning C (2006) A phosphatidic acid-binding protein of the chloroplast inner envelope membrane involved in lipid trafficking. Proc. Natl. Acad. Sci. USA 103: 10817-10822. Abstract
  30. Awai K, Kakimoto T, Awai C, Kaneko T, Nakamura Y, Takamiya K, Wada H and Ohta H (2006) Comparative genomic analysis revealed a gene for monoglucosyldiacylglycerol synthase, an enzyme for photosynthetic membrane lipid synthesis in cyanobacteria. Plant Physiol. 141: 1120-1127. Abstract
  31. Awai K, Xu C, Lu B and Benning C (2006) Lipid trafficking between the endoplasmic reticulum and the chloroplast. Biochem Soc Trans. 34:395-398. Abstract
  32. Xu C, Fan J, Froehlich J, Awai K and Benning C (2005) Mutation of an essential chloroplast envelope protein affects phosphatidate metabolism in Arabidopsis. Plant Cell 17: 3094-3110. Abstract
  33. Nakamura Y, Awai K, Masuda T, Yoshioka Y, Takamiya K and Ohta H (2005) A novel phosphatidylcholine-hydrolyzing phospholipase C that is induced during phosphate starvation in Arabidopsis. J. Biol. Chem. 280: 7469-7476. Abstract
  34. Kobayashi K, Awai K, Takamiya K and Ohta H (2004) Arabidopsis type B MGDG synthase genes are expressed during pollen tube growth and induced by phosphate starvation. Plant Physiol. 134: 640-648. Abstract
  35. Nakamura Y, Arimitsu H, Yamaryo Y, Awai K, Masuda T, Shimada H, Takamiya K and Ohta H (2003) Digalactosyldiacylglycerol is a major glycolipid in floral organs of Petunia hybrida. Lipids 38: 1107-1112. Abstract
  36. Yamaryo Y, Kanai D, Awai K, Shimojima M, Masuda T, Shimada H, Takamiya K and Ohta H (2003) Light and cytokinin play a cooperative role in MGDG synthesis in greening cucumber cotyledons. Plant Cell Physiol. 44: 844-855. Abstract
  37. Masuda T, Fusada N, Shiraishi T, Kuroda H, Awai K, Shimada H, Ohta H and Takamiya K (2002) Identification of two differentially regulated isoforms of protochlorophyllide oxidoreductase (POR) from tobacco revealed a wide variety of light- and development-dependent regulations of POR gene expression among angiosperms. Photosynth. Res. 74: 165-172. Abstract
  38. Awai K, Maréchal E, Block MA, Brun D, Masuda T, Shimada H, Takamiya K, Ohta H and Joyard J (2001) Two types of MGDG synthase genes, found widely in both “16:3” and “18:3” plants, differentially mediate galactolipid syntheses in photosynthetic and non-photosynthetic tissues in Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA. 98: 10960-10965. Abstract
  39. Sasaki Y, Asamizu E, Shibata D, Nakamura Y, Kaneko T, Awai K, Amagai M, Kuwata C, Tsugane T, Masuda T, Shimada H, Takamiya K, Ohta H and Tabata S (2001) Monitoring of methyl jasmonate-responsive genes in Arabidopsis by cDNA macroarray: Self-activation of jasmonic acid biosynthesis and crosstalk with other phytohormone signaling pathways. DNA Res. 8: 153-161. Abstract
  40. Gad M, Awai K, Shimojima M, Yamaryo Y, Shimada H, Masuda T, Takamiya K, Ikai A and Ohta H (2001) Accumulation of plant galactolipid affects cell morphology of Escherichia coli. Biochem. Biophys. Res. Commun. 286: 114-118. Abstract
  41. Oosawa N, Masuda T, Awai K, Fusada N, Shimada H, Ohta H and Takamiya K (2000) Identification of a novel light-inducible isoform of NADPH-protochlorophyllide oxidoreductase from Arabidopsis thaliana. FEBS Lett. 474: 133-136. Abstract
  42. Maréchal E, Awai K, Block MA, Brun D, Masuda T, Shimada H, Takamiya K, Ohta H and Joyard J (2000) The multigene family of monogalactosyl diacylglycerol synthases. Biochem. Soc. Trans. 28: 732-738. Abstract
  43. Yamaryo Y, Kanai D, Awai K, Masuda T, Shimada H, Takamiya K and Ohta H (2000) Transcriptional regulation by light and phytohormones of the MGD gene in cucumber. Biochem. Soc. Trans. 28: 738-740. Abstract
  44. Sasaki Y, Asamizu E, Shibata D, Nakamura Y, Kaneko T, Awai K, Masuda T, Shimada H, Takamiya K, Tabata S and Ohta H (2000) Genome-wide expression -monitoring of jasmonate-responsive genes of Arabidopsis using cDNA arrays. Biochem. Soc. Trans. 28: 863-864. Abstract
  45. Miège C, Maréchal E, Shimojima M, Awai K, Block MA, Ohta H, Takamiya K, Douce R and Joyard J (1999) Biochemical and topological properties of type A MGDG synthase, a spinach chloroplast envelope enzyme catalyzing the synthesis of both prokaryotic and eukaryotic MGDG. Eur. J. Biochem. 265: 990-1001. Abstract
  46. Ohta H, Suzuki G, Awai K, Masuda T, Kato T, Shibata D and Takamiya K (1997) Distinct pathway for jasmonate- and elicitor-induced expressions of a cytochrome P450 gene in soybean suspension-cultured cells. Physiol. Plant. 100: 647-652. Abstract



  1. Jouhet J, Shimojima M, Awai K and Marechal E (2021) Editorial: Lipids in Cyanobacteria, Algae, and Plants-From Biology to Biotechnology. Front Plant Sci. in press. Abstract
  2. 粟井光一郎(2021)光シアノバクテリアの脂質代謝 生物工学会誌 99(8): 404-407. pdf
  3. Iwai M, Shibata S, Ohta H and Awai K (2021) Methods of Lipid Analyses for Microalgae: Charophytes, Eustigmatophytes, and Euglenophytes. Methods Mol Biol. 2295: 81-97.  Abstract
  4. 小林滉宜,粟井光一郎(2018)光合成を担うナノ構造体,チラコイドの構築機構 オレオサイエンス 18: 241-247. pdf
  5. Apdila ET and Awai K (2017) Configuration of the sugar head of glycolipids in thylakoid membranes. Genes Genet. Syst. 92: 235-242. Abstract
  6. 日原由香子,朝山宗彦,蘆田弘樹,天尾豊,新井宗仁,粟井光一郎,得平茂樹,小山内崇,鞆達也,成川礼,蓮沼誠久,増川一(2017)多彩な戦略で挑むシアノバクテリア由来の燃料生産 持続可能な第三世代バイオ燃料生産の最前線 化学と生物 55: 88-97.
  7. Awai K (2016) Thylakoid Development and Galactolipid Synthesis in Cyanobacteria. Subcell Biochem. 86: 85-101. Abstract
  8. Sato N and Awai K (2016) Diversity in Biosynthetic Pathways of Galactolipids in the Light of Endosymbiotic Origin of Chloroplasts. Front Plant Sci. 7: 117 Abstract
  9. 粟井光一郎(2015)光合成生物におけるガラクト脂質合成経路の分布と進化  光合成研究 25: 143-150. 冊子pdf
  10. 成川礼、藤澤貴智、岡本忍、得平茂樹、吉村英尚、鈴木石根、増田建、持丸真里、高市真一、粟井光一郎、関根光雄、矢代勲、小俣せいは、宝田裕美、片野葉子、小杉大樹、谷河聡、大森和子、佐藤直樹、池内昌彦、藤田信之、大森正之(2010)産業的に重要なシアノバクテリアArthrospira platensis NIES-39(通称スピルリナ)のゲノムの多様な特徴:基礎から応用まで、個々の遺伝子から比較ゲノムまで 光合成研究 20: 150-160. 冊子pdf
  11. Awai K, Lechno-Yossef S and Wolk CP (2009) Heterocyst envelope glycolipids, In Lipids in Photosynthesis: Essential and Regulatory Functions (Wada, H. and Murata, N. eds), pp 179-202, Springer.
  12. 粟井光一郎(2009)光合成膜ガラクト脂質合成経路の多様性 光合成研究 19: 9-12. 冊子pdf
  13. 粟井光一郎(2006)葉緑体膜脂質合成に関わるマルチサブユニット型ABCトランスポーター 化学と生物 44: 731-732.
  14. Benning C, Xu C and Awai K (2006) Non-vesicular and vesicular lipid trafficking involving plastids. Curr Opin Plant Biol. 9: 241-247. Abstract
  15. Benning C, Xu C and Awai K (2004) Arabidopsis as a genetic model for interorganelle lipid trafficking. Genetic Engineering 26: 1-11.
  16. Ohta H, Awai K and Takamiya K (2000) Glyceroglycolipids of photosynthetic organisms -Their biosynthesis and evolutionary origin-. Trend. Glycosci. Glycotech. 12: 241-253.
  17. Ohta H, Shimojima M, Awai K, Masuda T and Takamiya K (1997) Glycolipids in chloroplast thylakoid membrane: The mechanism for the biosynthesis and evolutionary origin. Tanpakushitsu Kakusan Koso 42: 2601-2612.



  1. Awai K, Matsuoka R and Shioi Y (2012) Lipid and fatty acid compositions of Symbiodinium sp. Proceedings of the 12th International Coral Reef Symposium.
  2. Matsuoka R, Awai K and Shioi Y (2012) Pigment composition and pigment-protein complex from Symbiodinium sp. strain Y106. Proceedings of the 12th International Coral Reef Symposium.
  3. Ichikawa Y, Suzuki Y, Awai K and Shioi Y (2012) Characterization of VLK-protease from Symbiodinium sp. strain KB8. Proceedings of the 12th International Coral Reef Symposium.
  4. Awai K, Xu C, Lu B and Benning C (2007) Lipid trafficking between the endoplasmic reticulum and the chloroplast. In Current Advances in the Biochemistry and Cell Biology of Plant Lipids, Benning C and Ohlrogge J eds, pp 43-47, Aardvark Global Publishing Company, USA.
  5. Kobayashi K, Awai K, Shimada H, Masuda T, Takamiya K and Ohta H (2003) Histochemical analysis of three MGD genes using promoter-GUS fusion system in Arabidopsis. In Advanced Research on Plant Lipids, Murata, N., Yamada, M., Nishida, I., Okuyama, H., Sekiya, J., Hajime, W. eds, pp 199-202, Kluwer Academic Publishers, The Netherland.
  6. Fusada N, Oosawa N, Masuda T, Awai K, Shiraishi T, Shimada H, Ohta H, Ohto M, Nakamura K, Kato T, Tabata S and Takamiya K (2000) Identification and physiological role of a novel gene of NADPH-protochlorophyllide oxidoreductase in Arabidopsis thaliana. Porphyrins 9: 257-260.
  7. Ohta H, Shimojima M, Awai K, Kanai D, Masuda T and Takamiya K (1998) Plant MGDG synthases: their evolutionary aspects and light and hormonal control of the mRNA expression during developmental stage. In Advances in Plant Lipid Research, Sanchez, J., Cerda-Olmedo, E., Martinez-Force, E. eds, pp 367-370, Universidad de Sevilla, Secretariado de Publicaciones, Spain.
  8. Miège C, Maréchal E, Block MA, Shimojima M, Awai K, Ohta H, Takamiya K Joyard J (1998) Molecular identification of the MGDG synthase from spinach chloroplast envelope. In Advances in Plant Lipid Research, Sanchez, J., Cerda-Olmedo, E., Mar tinez-Force, E. eds, pp 247-250, Universidad de Sevilla, Secretariado de Publicaciones, Spain.