publication

原著論文・総説・著書

2018年

K. Hirakawa, T. Kaneko, and N. Toshima, “Kinetics of spontaneous bimetallization between silver and noble metal nanoparticles”, Chemistry – An Asian Journal, 13巻 (15号), 1892-1896頁, 2018年 (Front Cover).

M. E. Heo, Y.-A. Lee, K. Hirakawa, S. Okazaki, S. K. Kim, and D. W. Cho, “Sequence selective photoinduced electron transfer of a pyrene–porphyrin dyad to DNA”, Physical Chemistry Chemical Physics, 20巻, 16386-16392頁, 2018年.

K. Hirakawa, D. Ouyang, Y. Ibuki, S. Hirohara, S. Okazaki, E. Kono, N. Kanayama, J. Nakazaki, and H. Segawa, “Photosensitized protein-damaging activity, cytotoxicity, and antitumor effects of P(V)porphyrins using long-wavelength visible-light through electron transfer”, Chemical Research in Toxicology, 31巻, 371-379頁, 2018年.

K. Hirakawa and A. Murata, “Photosensitized oxidation of nicotinamide adenine dinucleotide by diethoxyphosphorus(V)tetraphenylporphyrin and its fluorinated derivative: Possibility of chain reaction”, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 188巻, 640-646頁, 2018年.

S. Ohnishi, Y. Hiraku, K. Hasegawa, K. Hirakawa, S. Oikawa, M. Murata, S. Kawanishi, “Mechanism of oxidative DNA damage induced by metabolites of carcinogenic naphthalene”, Mutation Research – Genetic Toxicology and Environmental Mutagenesis, 827巻, 42-49頁, 2018年.

K. Hirakawa and K. Sugimoto, “Redox Cycles of Benzenediol Derivatives Responsible for Hydrogen Peroxide Formation”, in: Reactive Oxygen Species (ROS): Mechanisms and Role in Health and Disease, ed. by Shannon Wilkerson, Nova Science Publishers, New York, ISBN: 978-1-53613-166-6, Chapter 9, pp. 295-310, 2018年.(著書)

K. Hirakawa, “Biomolecules Oxidation by Hydrogen Peroxide and Singlet Oxygen” in: Reactive Oxygen Species (ROS) in Living Cells, ed. by Filip Cristiana, Rijeka, Croatia, ISBN 978-953-51-5822-6, InTech Open. Chapter 9, pp. 161-189, 2018年.(著書)

伊藤, 植田, 梅本, 神田, 新部, 原田, 平川, 藤本, 宮林, 盛谷(五十音順), “演習・基礎から学ぶ大学の化学”, 培風館, 東京, ISBN: 978-4-563-04630-9C3043, 2018年.(教科書)

2017年

K. Hirakawa and T. Ishikawa, “Phenothiazine dyes photosensitize protein damage through electron transfer and singlet oxygen generation”, Dyes and Pigments, 142巻, 183-188頁, 2017年.

H. S. Lee, J. H. Han, J. H. Park, M. E. Heo, K. Hirakawa, S. K. Kim, and D. W. Cho, “Relationship between the photoinduced electron transfer and binding modes of a pyrene–porphyrin to DNA”, Physical Chemistry Chemical Physics, 19巻, 27123-27131頁, 2017年.

D. Ouyang and K. Hirakawa, “Photosensitized enzyme deactivation and protein oxidation by axial-substituted phosphorus(V) tetraphenylporphyrins”, Journal of Photochemistry and Photobiology, B: Biology, 175巻, 125-131頁, 2017年.

K. Hirakawa, A. Murata, and S. Okazaki, “Photosensitized biomolecule oxidation activity of ethoxy and fluoroethoxyP(V)porphyrins: a mini-review”, Photomedicine and Photobiology, 39巻, 19-20頁, 2017年.(英文総説)

K. Hirakawa, “Electron Transfer and Singlet Oxygen Mediated Mechanisms of Photodynamic Efect by P(V)porphyrins”, in: Spectroscopic Tools for the Diagnosis and Treatment of Cancer, ed. by N. Miyoshi, K. Hirakawa, and S. K. Kundu, SANKEISHA, Nagoya, ISBN: 978-4-86487-703-9, Chapter 1, pp. 4-14, 2017年.(著書)

K. Hirakawa and S. Okazaki, “Control of Photosensitized Singlet Oxygen Generation by Porphyrinss Using Interaction with DNA”, in: Spectroscopic Tools for the Diagnosis and Treatment of Cancer, ed. by N. Miyoshi, K. Hirakawa, and S. K. Kundu, SANKEISHA, Nagoya, ISBN: 978-4-86487-703-9, Chapter 2, pp. 15-25, 2017年.(著書)

K. Hirakawa, “Control of Fluorescence and Photosensitized Singlet Oxygen-Generating Activities of Porphyrins by DNA: Fundamentals for Theranostics”, in: Phthalocyanines and Some Current Applications, ed. by Yusuf Yilmaz, InTech – Open Access Publisher, Rijeka, Croatia, ISBN: 978-953-51-5372-6, Chapter 8, pp. 169-188, 2017年.(著書)

K. Hirakawa, “Folic acid demonstrates biomolecule photodamaging activity and potential chemopreventive action on phototoxicity”, in: Folic Acid: Sources, Health Effects and Role in Disease Prevention, Nova Science Publishers, New York, ISBN: 978-1-53611-820-9, Chapter 3, pp. 105-124, 2017年.(著書)

K. Hirakawa, “Photosensitizing activity of xanthone and chemopreventive action of its derivatives on phototoxicity” in: Advances in Medicine and Biology, Vol. 112, ed. by Leon V. Berhardt, Nova Science Publishers, New York, Chapter 8, pp. 207-222, ISBN: 978-1-53610-625-1, 2017年.(著書)

K. Hirakawa, “S2 fluorescence of metalloporphyrins and its applications for photochemical tools”, in: Advances in Chemistry Research. Volume 36, ed. by James C. Taylor, Nova Science Publishers, New York, Chapter 5, pp. 153-170, ISBN: 978-1-53610-781-4, 2017年.(著書)

2016年
K. Hirakawa and H. Segawa, “Multi-step intramolecular excitation energy transfer in dendritic pyrene-phosphorus(V)porphyrin heptads”, Journal of Luminescence, 179巻, 457-462頁, 2016年

K. Hirakawa and S. Morimoto, “Electron Transfer Mediated Decomposition of Folic Acid by Photoexcited Dimethoxophosphorus(V)porphyrin”, Journal of Photochemistry and Photobiology, A: Chemistry,318巻, 1-6頁, 2016年.

D. Ouyang, S. Inoue, S. Okazaki, and K. Hirakawa, “Tetrakis(N-methyl-p-pyridinio)porphyrin and its zinc complex can photosensitize damage of human serum albumin through electron transfer and singlet oxygen generation”, Journal of Porphyrins and Phthalocyanines, 20巻, 813-821頁, 2016年.

K. Hirakawa, M. Minamihori, and D. Ouyang, “UVA induced decomposition of folic acid and protein photodamaging activity of the decomposed products”, Photomedicine and Photobiology, 38巻, 27-28頁, 2016年.

D. Ouyang and K. Hirakawa, “Analysis of visible-light induced oxidative damage of proteins by phosphorus(V)porphyrin photosensitizer”, Photomedicine and Photobiology, 38巻, 25-26頁, 2016年.

K. Hirakawa, “Type I Photosensitizers for Cancer Therapy”, in Photosensitizers: Types, Uses and Selected Research, ed. by Cody Whitmire, Nova Science Publishers, New York, Chapter 1, pp.1-28, ISBN: 978-1-53610-173-7, 2016年.(著書)

2015年
K. Hirakawa, M. Taguchi, and S. Okazaki, “Relaxation Process of Photoexcited meso-Naphthylporphyrins while Interacting with DNA and Singlet Oxygen Generation”, The Journal of Physical Chemistry B, 119巻, 13071-13078頁, 2015年.

T. Ohtsuki, S. Miki, S. Kobayashi, T. Haraguchi, E. Nakata, K. Hirakawa, K. Sumita, K. Watanabe, S. Okazaki, “The molecular mechanism of photochemical internalization of cell penetrating peptide-cargo-photosensitizer conjugates”, Scientific Reports, DOI: 10.1038/srep18577, 1-9頁, 2015年.

K. Hirakawa, H. Umemoto, R. Kikuchi, H. Yamaguchi, Y. Nishimura, T. Arai, S. Okazaki, and H. Segawa, “Determination of singlet oxygen and electron transfer mediated mechanisms of photosensitized protein damage by phosphorus(V)porphyrins”, Chemical Research in Toxicology, 28巻, 262-267頁, 2015年.

K. Hirakawa and T. Yoshioka, “Photoexcited riboflavin induces oxidative damage to human serum albumin”, Chemical Physics Letters, 634巻, 221-224頁, 2015年.

K. Hirakawa and H. Ito, “Rhodamine-6G can photosensitize folic acid decomposition through electron transfer”, Chemical Physics Letters, 627巻, 26-29頁, 2015年

K. Hirakawa, S. Aoki, H. Ueda, D. Ouyang, and S. Okazaki, “Photochemical property and photodynamic activity of tetrakis(2-naphthyl) porphyrin phosphorus(V) complex”, Rapid Communication in Photoscience, 4巻, 37-40頁, 2015.

R. Makita, M. Yamashita, M. Yamaoka, M. Fujie, S. Nakamura, T. Oshikawa, J. Yamashita, M. Yamada, K. Asai, T. Suyama, M. Kondo, H. Hasegawa, Y. Okita, K. Hirakawa, M. Toda, K. Ohnishi, and H. Sugimura, “Novel multiple type molecular targeted antitumor agents: preparation and preclinical evaluation of low-molecular-weight phospha sugar derivatives”, Phosphorus, Sulfur, and Silicon and the Related Elements, 190巻, 733-740頁, 2015年.

D. Ouyang and K. Hirakawa, “Photosensitized oxidative damage of human serum albumin by water-soluble dichlorophosphorus(V) tetraphenylporphyrin”, Rapid Communication in Photoscience, 4巻, 41-44頁,2015年.

K. Hirakawa, “Electron transfer-mediated photodynamic therapy in hypoxic condition”, Photomedicine and Photobiology, 37巻, 19-20頁, 2015年.

平川, “葉酸の光化学”, 光化学, Vol. 46, No. 3, 161-164頁, 2015年.(和文総説)

J. Matsumoto, T. Shiragami, K. Hirakawa, and M. Yasuda, “Water-solubilization of P(V) and Sb(V) porphyrin and their photobiological application”, International Journal of Photoenergy, doi:10.1155/2015/148964, Vol. 2015, 1-12頁, 2015年.(英文総説)

K. Hirakawa, “Fundamentals of medicinal application of titanium dioxide nanoparticles”, in Nanoparticles Technology, ed. by Mahmood Aliofkhazraei, InTech – Open Access Publisher, Rijeka, Croatia, Chapter 2, pp. 13-32, ISBN 978-953-51-0500-8, 2015年.(著書)

K. Hirakawa, “Fundamentals of singlet oxygen, ozone, and Hydrogen peroxide for engineering”, in: Advances in Engineering Research 10, ed by Victoria M. Petrova, Nova Science Publishers, New York, Chapter 7, pp.153-162, ISBN: 978-1-63482-784-3, 2015年.(著書)

K. Hirakawa, “Using folic acids to detect reactive oxygen species”, in: Advances in Chemistry Research. Volume 26, ed. by James C. Taylor, Nova Science Publishers, New York, Chapter 7, pp.111-126, ISBN: 978-1-63463-630-8, 2015年.(著書)

K. Hirakawa, “Computational Chemistry for Photosensitizer Design and Investigation of DNA Damage”, in Frontiers in Computational Chemistry, Vol. 2, ed. by Zaheer-ul-Haq and J. D. Madura, Elsevier (Bentham Science Publishers), Chapter 2, pp. 33-76, ISBN: 978-1-60805-979-9, 2015年.(著書)

2014年
K. Hirakawa, K. Ota, J. Hirayama, S. Oikawa, and S. Kawanishi, “Nile blue can photosensitize DNA damage through electron transfer”, Chemical Research in Toxicology, 27巻, 649-655頁, 2014年.

K. Hirakawa and S. Nakajima, “Effect of DNA microenvironment on photosensitized reaction of water-soluble cationic porphyrins”, Recent Advances in DNA and Gene Sequences, 8巻, 35-43頁, 2014年.

J. Fujisawa and K. Hirakawa, “Mechanisms of large red-shift and intensity enhancement of absorption bands by π-bond breaking in a verteporfin sensitizer for photodynamic therapy”, Journal of Porphyrins and Phthalocyanines, 18巻, 513-518頁, 2014年.

K. Hirakawa and M. Yoshida, “Theoretical study of the effects of amino acids on one-electron oxidation of a nucleobase: adenine residue can be a hole-trapping site”, Pure and Applied Chemical Sciences, 2巻, 41-48頁, 2014年.

K. Hirakawa, Y. Ito, T.i Yamada, and S. Okazaki, “Relaxation process of the photoexcited state and singlet oxygen generating activity of water-soluble meso-phenanthrylporphyrin in a DNA microenvironment”, Rapid Communication in Photoscience, 3巻, 81-84 頁, 2014年.

K. Hirakawa, Y. Yamaji, T. Yonezawa, and N. Toshima, “Reduction of carbon dioxide using a visible-light-induced electron transfer system with colloidal metal nanoparticle catalysts: evidence for production of methane”, Current Topics in Catalysis, 11巻, 55-63頁, 2014年.

K. Hirakawa and T. Suzuki, “Amino acids photocatalyzed by titanium dioxide can produce secondary hydrogen peroxide”, Trends in Photochemistry and Photobiology, 16巻, 63-69頁, 2014年.

酸素,オゾンの光化学, 4章4.2④, 156頁, 酸素含有化合物, 光化学の辞典, 光化学協会光化学の事典編集委員会 編、朝倉書店, ISBN978-4-254-14096-5 C3543, 2014年.(著書)

2013年
K. Hirakawa, Y. Nishimura, T. Arai, and S. Okazaki, “Singlet oxygen generating activity of an electron donor-connecting porphyrin photosensitizer can be controlled by DNA”, The Journal of Physical Chemistry B, 117巻, 13490-13496頁, 2013年.

K. Hirakawa, T. Yamanaka, J. Matsumoto, and M. Yasuda, “Examination of protein-damaging activity of phosphorus(V)porphyrin photosensitizer for photodynamic therapy”, Journal of Analytical and Bioanalytical Techniques, .1-5頁, 2013年.

K. Hirakawa, N. Fukunaga, Y. Nishimura, T. Arai, and S. Okazaki, “Photosensitized protein damage by dimethoxyphosphorus(V) tetraphenylporphyrin”, Bioorganic & Medicinal Chemistry Letters, 23巻, 2704-2707頁, 2013年.

K. Hirakawa, K. Azumi, Y. Nishimura, T. Arai, Y. Nosaka, and S. Okazaki, “Photosensitized damage of protein by fluorinated diethoxyphosphorus(V)porphyrin”, Journal of Porphyrins and Phthalocyanines, 17巻, 56-62頁, 2013年.

K. Hirakawa, “Photo-energy and electron donating ability of pyrene”, in Pyrene: Chemical Properties, Biochemistry Applications and Toxic Effects, ed. by Petr Ruzicka and Tomas Kral, Nova Science Publishers, Chapter 5, pp. 141-166, New York, ISBN: 978-1-62417-291-5, 2013年.(著書)

2012年
K. Hirakawa, M. Harada, S.i Okazaki, and Y. Nosaka, “Controlled Generation of Singlet Oxygen by a Water-soluble meso-Pyrenylporphyrin Photosensitizer through Interaction with DNA”, Chemical Communications, 48 巻, 4770-4772頁, 2012年.

K. Hirakawa T. Hirano, Y.Nishimura, T. Arai, and Y. Nosaka, “Dynamics of Singlet Oxygen Generation by DNA-binding Photosensitizers”, The Journal of Physical Chemistry B, 116巻, 3037-3044頁, 2012年.

K. Hirakawa, “Titanium dioxide photocatalyzes DNA damage via the secondary generation of hydrogen peroxide in the presence of sugars”, Trends in Photochemistry and Photobiology, 14巻, 69-73頁, 2012年.

K. Hirakawa and S. Inoue, “Analysis of protein damage based on the fluorometry of tryptophan residue”, Current Topics in Analytical Chemistry, 9巻, 57-62頁, 2012年.

K. Hirakawa, “Phosphorus complex of porphyrins”, in Phosphorus: Properties, Health Effects and the Environment, ed. by, Ming Yue Chen and Da-Xia Yang, Nova Science Publishers, New York, Chapter 7, pp. 179-193, ISBN: 978-1-62081-399-7, 2012年.(著書)

K. Hirakawa, “Phosphorus(V)porphyrin: Its Potential Application for Photomedicine”, in Handbook of Porphyrins: Chemistry, Properties and Applications, ed. by Ayumu Kaibara and Genji Matsumara, Nova Science Publishers, New York, Chapter 12, pp. 393-408, ISBN: 978-1-62081-068-2, 2012年.(著書)

K. Hirakawa, “Self-organization of Silver-core Bimetallic Nanoparticles and Their Application for Catalytic Reaction” in Smart Nanoparticles Technology, ed. by Abbass Hashim, InTech – Open Access Publisher, Rijeka, Croatia, Chapter 4, pp. 67-92, ISBN: 978-953-51-0500-8, 2012年.(著書)

K. Hirakawa, “Photochemical Experiments in Acetonitrile” in Acetonitrile: Properties, Applications and Health Effects, ed. by Iyeremey Demeter and Emanuil Itsov, Nova Science Publishers, New York, Chapter 6, pp. 109-120, ISBN: 978-1-61942-189-9, 2012年.(著書)

K. Hirakawa, “Photobiological Properties of Folic Acid and Its Application”, in Folic Acid: Properties, Medical Uses and Health Benefits, ed. by Mária Szabó and Eve Varga, Chapter 7, pp. 165-190, ISBN: 978-1-62100-867-5, Nova Science Publishers, New York, 2012年.(著書)

2011年
K. Hirakawa, S. Ochiai, S. Oikawa, and S. Kawanishi, “Oxygen-independent DNA damage photosensitized by rhodamine-6G”, Trends in Photochemistry and Photobiology, 13巻, 29-35頁, 2011年.

K. Hirakawa, T. Hirano, Y. Nishimura, T. Arai, and Y. Nosaka, “Control of Singlet Oxygen Generation Photosensitized by meso-Anthrylporphyrin through Interaction with DNA”, Photochemistry and Photobiology, 87巻, 833-839頁, 2011年.

J. Matsumoto, T. Shinbara, S. Tanimura, T. Matsumoto, T. Shiragami, H. Yokoi, Y.Nosaka, S. Okazaki, K. Hirakawa, and M. Yasuda, “Water-soluble phosphrousporphyrins with high activity for visible light-assisted inactivation of Saccharomyces cerevisiae”, Journal of Photochemistry and Photobiology, A: Chemistry, 218巻, 178-184頁, 2011年.

K. Hirakawa, H. Segawa, T. Hirano, S. Okazaki, and Y. Nosaka, “Protein oxidation through oxygen-independent mechanism by P(V)porphyrin photosensitizer” in “In hope of going over the present Clinical PD and PDT” ed. by N. Miyoshi and R. H. Pottier, SANKEISHA CO. LTD., Nagoya, Chapter 4, pp. 40-50, ISBN978-4-88361-883-5-C3047, 2011年.(著書)

K. Hirakawa, and T. Hirano, “Photocatalyzed Singlet Oxygen Formation by Titanium Dioxide and Its Phototoxic Effect” in “In hope of going over the present Clinical PD and PDT” ed. by N. Miyoshi and R. H. Pottier, SANKEISHA CO. LTD., Nagoya, Chapter 5, pp. 51-62, ISBN978-4-88361-883-5-C3047, 2011年.(著書)

K. Hirakawa, and T. Hirano, “Development of DNA selective porphyrinoid photosensitizer” in “In hope of going over the present Clinical PD and PDT” ed. by N. Miyoshi and R. H. Pottier, SANKEISHA CO. LTD., Nagoya, Chapter 6, pp. 63-75, ISBN978-4-88361-883-5-C3047, 2011年.(著書)

K. Hirakawa, “Deuterium Effect on the Photosensitized Biomolecules Damage via Singlet Oxygen Generation”, in “Advances in Chemistry Research. Volume 10” ed. by James C. Taylor, Nova Science Publishers, New York, Chapter 16, ISBN: 978-1-61324-018-2, pp. 429-437, 2011年.(著書)

植田, 梅本, 平川, 山田(五十音順), 基礎から学ぶ大学の化学, 培風館, 2011.(教科書)

2010
K. Hirakawa and H.Segawa, “Effects of Hydrogen Bonding Interaction and Solvent Polarity on the Competition between Excitation Energy and Photo-induced Electron Transfer Processes in Hydroxy(1-pyrenebutoxy)phosphorus(V)porphyrin”, Journal of Photochemistry and Photobiology, A: Chemistry, 213巻, 73-79頁, 2010年.

K.Hirakawa and H.i Segawa, “Tetra(p-t-butyl)thiacalix[4]arenetetrol Forms 4:1 Complex with Tetrakis(1-methyl-4-pyridinio)porphyrin”, Bulletin of the Chemical Society of Japan, 83巻, No. 7, 828-830頁, 2010年.

K. Hirakawa and H. Segawa, “Acid Dissociation of Axial Hydroxyl Group of Hydroxy(1-pyrenebutoxy)-phosphorus(V) Porphyrin Controls the Intramolecular Excitation Energy Transfer”, Photochemical and Photobiological Sciences, 9巻, 704-709頁, 2010年.

K. Hirakawa, “Chemopreventive action of organic and inorganic materials on phototoxic effect”, in “Photobiology: Principles, Applications and Effects” ed by Léon N. Collignon and Claud B. Normand, Nova Science Publishers, New York, Chapter 6, ISBN: 978-1-61668-005-3, pp. 137-158, 2010.

生駒, 植田, 梅本, 平川, 山田(五十音順), 工学基礎化学実験、学術図書出版社, 2010.(教科書)

2009年以前
整理中