新しい有機化学反応の開発と有用生理活性物質合成への応用
(a) C2軸不斉化合物を用いた新しい分子制御法の開発
(b) 天然資源（糖、アミノ酸など）由来のカイロンを利用した新しい立体識別法の開発
(c) 高次連続不斉化合物の短段階合成
(d) 高度酸化化合物の還元反応を経由する高効率的官能基化
(e) ランタノイド化合物を用いた不斉有機反応の開発
最近研究室で合成したスピロ環状化合物
最近研究室で開発された新規な反応
2017年
Use of β-Amido Allylboronate as a Nucleophilic Reagent in Catalytic Enantioselective Addition to Isatins
European Journal of Organic Chemistry, 2017, 1285-1288.
2015年
Indium-catalyzed Amide Allylation of N-carbonyl Imides: Formation of Azaspiro-γ-lactones via Ring Opening-reclosure
Organic Letters 2015, 17, 5846-5849.
Synthesis of New Chiral Lactam–fused Pyridine Derivatives
RSC Advances 2015, 5, 73562-73565.
2014年
Catalytic Amide Allylation of Alpha-ketoester: Extremely High Enantioselective Synthesis of ester functionalised Alpha-methylene-gamma-butyrolactones
Organic & Biomolecular Chemistry, 2014, 12, 7686-7689.
2013年
Construction of Spiro-Fused 2-Oxindole/ α-Methylene-γ-Butyrolactone Systems with Extremely High Enantioselectivity via Indium-Catalyzed Amide Allylation of N-Methyl Isatin
Organic Letters, 2013, 15, 6182-6185.
Synthetic approach toward α-aminomethyl-γ-butyrolactones from β-lactam synthons elaborated by SmI2-mediated reductive coupling reactions.
Natural Product Communications 2013, 8, 889-896.
2012年
A Synthetic Approach to Diverse 3-Acyltetramic Acids via O– to C-Acyl Rearrangement and Application to the Total Synthesis of Penicillenol Series
The Journal of Organic Chemistry, 2012, 77, 4391-4401.
2011年
New Synthetic Methodology toward Macrolides/Macrolactams via Palladium-Catalyzed Carbon-Heteroatom Bond-Forming Reactions
Synlett, 2011, 1766-1768.
2010年
Synthesis of b-Amino-functionalized a-exo-Methylene–g-butyrolactones via a b-Lactam Synthon Strategy
Synthesis 2010, 42, 3282-3288.
2009年
Extremely High Regio- and Stereoselective C-C Bond Formation of Substituted γ-hydroxylactams: Synthesis of Macronecines Based on Their Structural Duality
Tetrahedron, 2009, 65, 2415-2423.
2006年
Novel Chemoselective Desulfurization of γ-Phenylthio-substituted Aromatic Lactams: Application to the Synthesis of Isoindolobenzazepine Alkaloid, Lennoxamine
Synlett, 2006, 3407-3410.
SmI2-promoted Novel Tandem Elimination and Coupling Reactions of Aliphatic Imides with Carbonyl Compounds; Application to the Synthesis of dl-Isoretronecanol
Tetrahedron Letters, 2006, 47, 1607-1611.
2000～2006年
