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Publications

2026

44. Amide-to-Chloroalkene Substitution for Peptide Backbone Modification to Enhance Membrane Permeability. Takeo, S., Takeda, M., Iio, C., Sakakibara, A., Saha, S., Shibata, N., Yamazaki, Y., Fujii, T., Harada, R., Sato, K., Mase, N., Watanabe, M., Oyoshi, T., Narumi, T. J. Med. Chem. 2026, 

43. Transcriptional regulation of telomeric repeat-containing RNA by the G-quadruplex-binding Ewing sarcoma protein. Ulum, L. L., Matsudaira, W., Yamanashi, M., Shibata, N., Saha, S., Ishihara, A., Oyoshi, T. Sci. Rep. 2026, 16, 715.

42. A Stable Bioisostere of Ester-Linked Ubiquitin Chains Enables Decoding of Protein Interactors. Taguchi, Y., Tomita, T., Nishizawa, T., Nakamura, D., Saha, S., Oyoshi, T., Sato, K., Mase, N., Saeki, Y., Narumi, T. ChemBioChem 2026, 27, e202500749.

2025

41. Influence of DNA topology on the photoreactions of various psoralen derivatives with duplex DNAs. Amin, M. A., Senda, R., Hisatomi, K., Fujimoto, K., Oyoshi, T. Chem. Lett. 2025, 54, upaf232.

40. Identification of Guanine-Quadruplex-Binding Peptides from the RGG3 Domain of TLS/FUS. Takeo, S., Tabata, M., Okita, H., Shibata, N., Sato, K., Mase, N., Oyoshi, T., Narumi, T. Chem. Pharm. Bull. 2025, 73, 938-943.

2023

39. DNA G‐Quadruplex-Binding Protein Developed Using the RGG Domain of Translocated in Liposarcoma/Fused in Sarcoma Inhibits Transcription of bcl‐2. Ulum, L. L., Karikome, Y., Yagi, R., Kawashima, T., Ishihara, A., Oyoshi, T. ACS Omega 2023, 8, 10459-10465.

38. Bovine Serum Albumin Hydrogel Formation: pH Dependence and Rheological Analyses. Kimura, S., Komiyama, T., Masuzawa, T., Yokoya, M., Oyoshi, T., Yamanaka, M. Chem. Pharm. Bull. 2023, 71, 229-233.

2021

37. Recognition of G-quadruplex RNA by a crucial RNA methyltransferase component, METTL 14. Yoshida, A., Oyoshi, T., Suda, A., Futaki, S., Imanishi, M. Nucleic Acids Res. 2021, 50, 449-457.

2020

36. G-quadruplex-proximity protein labeling based on peroxidase activity. Masuzawa, T., Sato, S., Niwa, T., Taguchi, H., Nakamura, H., Oyoshi, T. Chem. Commun.  2020, 56, 11641-11644.

35. Modulation of histone modifications and G-quadruplex structures by G-quadruplex-binding proteins. Oyoshi, T., Masuzawa, T. Biochem. Biophys. Res. Commun. 2020, 531, 39-44.

34. Stereoselective synthesis of Gly-Gly-type (E)-methylalkene and (Z)-chloroalkene dipeptide isosteres and their application to 14-mer RGG peptidomimetics. Okita, H., Kato, Y., Masuzawa, T., Arai, K., Takeo, S., Sato, K., Mase, N., Oyoshi, T., Narumi, T. RSC Adv. 2020, 10, 29373-29377.

33. Oligonucleotide DNA containing 8-trifuoromethyl-2'-deoxyguanosine for observing Z-DNA structure. Bao, H.-L., Masuzawa, T., Oyoshi, T., Xu, Y. Nucleic Acids Res. 2020, 48, 7041-7051.

32. Roles of the RGG domain and RNA recognition motif of Nucleolin in G‑quadruplex stabilization. Masuzawa, T., Oyoshi, T. ACS Omega 2020, 5, 5202-5208.

31. RNA sequence and length contribute to RNA-induced conformational change of TLS/FUS. Hamad, N., Mashima, T., Yamaoka, Y., Kondo, K., Yoneda, R., Oyoshi, T., Kurokawa, R., Nagata, T., Katahira, M. Sci. Rep. 2020, 10, 2629.

2019

30. Heterologous production of coryneazolicin in Escherichia coli. Takuma, M., Kuroha, M., Nagano, Y., Kaweewan, I., Hemmin, H., Oyoshi, T., Kodani, S. J. Antibiot. 2019, 72, 800-806.

29. Isolation and structure determination of a new cytotoxic peptide, curacozole, from Streptomyces curacoi based on genome mining. Kaweenwan, I., Komaki, H., Kemmi, H., Hoshino, K., Hosaka, T., Isokawa, G., Oyoshi, T., Kodani, S. J. Antibiot. 2019, 72, 1-7.

2018

28. G-quadruplex Binding Ability of TLS/FUS Depends on the β-Spiral Structure of the RGG Domain. Yagi, R., Miyazaki, T., Oyoshi, T. Nucleic Acids Res. 2018, 46, 5894-5901.

27. Multiplicity in long noncoding RNA in living cells. Kuorkawa, R., Komiya, R., Oyoshi, T., Matsuno, Y., Tani, H., Katahira, M., Hitachi, K., Iwashita, Y., Yamashita, T., Kondo, K., Yamaoki, Y., Ueda, N., Mashima, T., Kobayashi, N., Nagata, T., Kiyoishi, A., Miyake, M., Kano, F., Murata, M., Hamad, N., Sasaki, K., Shoji, N. Biomedical Sciences 2018, 4, 18-23.

26. Plastic roles of phenylalanine and tyrosine residues of TLS/FUS in complex formation with the G-quadruplexes of telomeric DNA and TERRA. Kondo, K., Mashima, T., Oyoshi, T., Yagi, R., Kurokawa, R., Kobayashi, N., Nagata, T., Katahira, M. Sci. Rep. 2018, 8, 2864. 

2017

25. Epigenetics regulated by DNA damage repair protein TLS/FUS. Oyoshi, T., Kino, K. Radiation Biology Research Communications. 2017, 52, 227-238.24. Bcl-XL-binding helical peptides possessing D-Ala residues at their C-termini with the advantage of long-lasting intracelluar stabilities. Nogami, K., Tokumaru, H., Isokawa, G., Oyoshi, T., Fujimoto, K., Inouye, M. Chem Commun. 2017, 53, 12104-12107. 23. Supramolecular gel electrophoresis of large DNA fragment. Tazawa, S., Kobayashi, K., Oyoshi, T., Yamanaka, M. Electrophoresis. 2017, 38, 2662-2665. 

22. A simple and sensitive 19F NMR approach for studying the interaction of RNA G-quadruplex with ligand molecule and protein. Bao, H.L., Ishizuka, T., Iwanami, A., Oyoshi, T., Xu, Y. ChemistrySelect. 2017, 2, 4170-4175. 

2016

21. Contiguous 2,2,4-triamino-5(2H)-oxazolone obstructs DNA synthesis by DNA polymerases α, β, η, ι, κ, REV1, and Klenow Fragment exo-, but not by DNA polymerase ζ. Suzuki, M., Kino, K., Kawada, T., Oyoshi, T., Morikawa, N., Kobayashi, T., Miyazawa, H. J. Biochem. 2016, 159, 323-329.

2015

20. G-quadruplex DNA- and RNA-specific-binding proteins engineered from the RGG domain of TLS/FUS. Takahama, K., Miyawaki, A., Shitara, T., Mitsuya, K., Morikawa, M., Hagihara, M., Kino, K., Yamamoto, A., Oyoshi, T. ACS Chem. Biol. 2015, 10, 2564-2569. 

19. Characterization of G-quadruplex DNA- and RNA-binding protein. Oyoshi, T., Long Noncoding RNAs 2015, 57-65.

18. Assessing the biological relevance of G-quadruplexs in telomeres by specific quadruplex-binding proteins. Oyoshi, T. Biological relevance & therapeutic applications of DNA- & RNA-quadruplexes 2015, 72-83.

17. Calculation of the HOMO localization of Tetrahymena and Oxytricha telomeric quadruplex DNA. Morikawa, M., Kino, K., Oyoshi, T., Suzuki, M., Kobayashi, T., Miyazawa, H. Bioorg. Med. Chem. Lett. 2015, 25, 3359-3362.

2014

16. Tailor-made designer helical peptides inducing mitochondrial cell death without necrosis. Nogami, K., Takahama, K., Okushima, A., Oyoshi, T., Fujimoto, K., Inouye, M. ChemBioChem 15, 2571-2576, 2014.

15. Supramolecular gel electrophoresis of acidic native proteins. Munenobu, K., Hase, T., Oyoshi, T., Yamanaka, M. Anal. Chem. 86, 9924-9929, 2014.

14. Analusis of guanine oxidation products in double-stranded DNA and proposed guanine oxidation pathway in single-stranded, double-straned or quadruplex DNA. Morikawa, M., Kino, K., Oyoshi, T., Suzuki, M., Kobayashia, T., Miyazawa, H. Biomolecules 4, 140-159, 2014.

2013

13. Product analysis of photooxidation in isolated quadruplex DNA; 8-oxo-7,8-dihydroguanine and its oxidation product at 3’-G are formed instead of 2,5-diamino-4H-imidazol-4-one. Morikawa, M., Kino, K., Oyoshi, T., Suzuki, M., Kobayashia, T., Miyazawa, H. RSC Adv. 3, 25694-25697, 2013.

12. Specific binding of modified RGG domain in TLS/FUS to G-quadruplex RNA: Tyrosines in RGG domain recognize 2’-OH of the riboses of loops in G-quadruplex. Takahama, K., Oyoshi, T. J. Am. Chem. Soc. 135, 18016-18019, 2013.

11. Regulation of Telomere Length by G-Quadruplex Telomere DNA- and TERRA-Binding Protein TLS/FUS. Takahama, K., Takada, A., Tada, S., Shimizu, M., Sayama, K., Kurokawa, R., Oyoshi, T. Chem. Biol. 20, 341-350, 2013.

2012

10. Structure of noncoding RNA is a determinant of function of RNA is a determinant of function of RNA binding proteins in transcriptional. Oyoshi,T., Kurokawa R. Cell Biosci., 2, 1, 2012

2011

9. Separation of proteins using supramolecular gel electrophoresis. Yamamichi, S., Jinno, Y., Haraya, N., Oyoshi, T., Tomitori, H., Kashiwagi, K., Yamanaka, M. Chem. Commun., 47, 10344-10346, 2011

8. Loop lengths of G-quadruplex structures affect the G-quadruplex DNA binding selectivity of the RGG motif in Ewing’s sarcoma. Takahama, K., Sugimoto, C., Arai, S., Kurokawa, R., Oyoshi, T. Biochemistry, 50, 5369-5378, 2011

7. Identification of Ewing’s sarcoma protein as a G-quadruplex DNA- and RNA-binding protein. Takahama, K., Kino, K., Arai, S., Kurokawa, R., Oyoshi, T. FEBS. J., 278, 988-998, 2011 

2004

6. Sequence-specific gene silencing in mammalian cells by alkylating pyrrole-imidazole polyamides. Shinohara, K., Narita, A., Oyoshi, T., Bando, T., Teraoka H., Sugiyama, H. J. Am. Chem. Soc. 126, 5113-5118, 2004

2003

5. Inhibition of Transcription at a Coding Sequence by Alkylating Polyamide. Oyoshi, T., Kawakami, W., Narita, A., Bando, T., Sugiyama, H. J. Am. Chem. Soc. 125, 4752-4754, 2003

4. Efficient C2’alpha-Hydroxylation of Deoxyribose in Protein-Induced Z-Form DNA. Oyoshi, T., Kawai, K., Sugiyama, H. J. Am. Chem. Soc. 125, 1526-1531, 2003

3. Deglyco-Peplomycin Metal Complexes on DNA-Fibers: A Role of the Sugar Moiety for the Stability and the Orientation of the Complexes. Iiyama, T., Chikira, M., Oyoshi, T., Sugiyama, H. J. Bio. Inorg. Chem. 8, 135-140, 2003

2002

2. Photoreactivity of 5-Iodouracil-Containing DNA-Sso7d Complex in Solution: The Protein-induced DNA Kink Causes Intrastrand Hydrogen Abstraction from the 5-Methyl of Thymine at the 5’ side. Oyoshi, T., Wang, A. H.-J., Sugiyama, H. J. Am. Chem. Soc. 124, 2086-2087, 2002

2000

1. Mechanism of DNA Strand Scission Induced by (1,10-Phenanthroline)copper: Major Direct DNA Cleavage Is Not through 1’,2’-Dehydronucletide Intermediate nor β-Elimination of Forming Ribonolactone. Oyoshi,T., Sugiyama, H. J. Am. Chem. Soc. 122, 6313-6314, 2000