Electrophilic amide allylation of 3-heterosubstituted oxindoles: a new route to spirocyclic 2-oxindole containing α-methylene-γ-butyrolactam structure
Tetsuya Sengoku, Daichi Hayashi, Masaki Takahashi and Hidemi Yoda
European Journal of Organic Chemistry, 2018, 1813-1820. ()
The key “electrophilic amide allylation” was accomplished by using acetoxy methacrylamides and tetrakis(triphenylphosphine)palladium as a catalyst, affording a variety of the amide allylated products in excellent yields.
Journal Information: Impact factor 2.834 (Q2, JCR 2016)